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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

AKAP1 binds KCND2. 2 / 2

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"It was previously shown that A-kinase anchoring proteins interact with Kv4.2 channels, which mediate the backpropagation of action potentials, in order to enhance their surface expression xref and that the turnover of Kv4.2 channels is regulated by PKA in distal dendrites of CA1 pyramidal cells xref ."

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"Moreover, Kv4.2 is associated with A-kinase anchored proteins or AKAPs, which may allow for efficient coupling between PKA activation and Kv4.2 modulation [ xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...