IndraLab

Statements


5 | 3

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"The physiological significance of the interaction of RAP80 with UBC9 and whether this interaction has any relevance to DDR signaling needs further investigation.Recent studies have demonstrated that R[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"These observations suggested that RAP80 might be a candidate for targeting BRCA1–BARD1BRCC36 complexes to DSB sites.In addition to two putative zinc finger motifs, RAP80 contains two UIMs at its amin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"These observations indicate that RAP80 has a regulatory function in DNA damage response signaling, probably by facilitating the recruitment of BRCA1–BARD1BRCC36 complexes to DNA damage foci."

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