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BAAT inhibits USP2. 2 / 2
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"Intriguingly, we noticed that there were 16 proteins that were completely absent in the Usp2 knockdown BAT (Figure 6D)."
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"Among these proteins, EBF2 has been demonstrated as the pivotal regulatory role in the development of brown adipose and adaptive thermogenesis [32], which piqued our interest.Indeed, RT-qPCR and western blot analysis of EBF2 showed that the protein levels of EBF2 were significantly decreased in the Usp2 knockdown BAT compared to controls, with comparable mRNA levels of Ebf2 (Figure 6E,F)."
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