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"In DMBA-treated skin cancer bearing female CD-1 mice, a maximal ingestion of 25 μmol resveratrol for 18 weeks two times/week downregulated COX-1, COX-2, c-Myc, c-Fos, c-Jun, TGF- β and TNF-α and reduc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"At the highest dose tested , resveratrol dramatically reduced c-Fos expression and completely suppressed TGF-beta1 expression ."
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"Moreover, resveratrol inhibited TPA-induced oxidative stress, expression and activity of pro-inflammatory enzyme cyclooxygenase-2 (COX-2), and transactivation of c-fos in mouse skin in vivo [13–15] ."