IndraLab

Statements


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"In addition, physalin F suppressed NF-kappaB activity and nuclear translocation of p65 and p50, which was reversed by NAC and GSH."

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"In addition, physalin F abrogated the nuclear translocation of p65 and p50 subunits that were reversed by both ROS scavengers, NAC and GSH (XREF_FIG)."

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"P65 is directly inhibited upon modification by glutathione [85], but glutathione can also oxidize IκBα at Cys189, causing its stabilization and indirect NF-κB inhibition [86]."