IndraLab

Statements

Glutathione inhibits RELA. 4 / 4
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" What is more, the increase in Nrf2 activity in lupus nephritis leads to the accumulation of glutathione (GSH), which effectively buffers free radicals and prevents the activation of p65, resulting in reduced deposition of extracellular matrix [28]."
26551702
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"P65 is directly inhibited upon modification by glutathione [85], but glutathione can also oxidize IκBα at Cys189, causing its stabilization and indirect NF-κB inhibition [86]."
32053878
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"In addition, physalin F abrogated the nuclear translocation of p65 and p50 subunits that were reversed by both ROS scavengers, NAC and GSH (XREF_FIG)."
22815798
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"In addition, physalin F suppressed NF-kappaB activity and nuclear translocation of p65 and p50, which was reversed by NAC and GSH."
22815798