IndraLab

Statements

BRAF-V599E is kinase-active. 1 / 1

1 |

"V599EB-Raf possesses the hallmarks of a conventional oncogene because the kinase activity of its encoded protein is greatly elevated; it constitutively stimulates ERK in vivo in the absence of Ras activation; and it transforms NIH3T3 cells.144"

16170185

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

BRAF-V599E is kinase-active. 1 / 1

INDRA sources:

Databases

Reading