IndraLab
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"In line with such a mechanism for USP44 induction in Tregs, and the findings obtained in our reporter system, T cells from mice genetically deficient in SMAD2 and SMAD3 fail to up-regulate USP44 under iTreg skewing conditions, and SMAD deficiency similarly abrogated USP44 up-regulation by iTregs (Fig XREF_FIG G)."