IndraLab

Statements


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"In control mice, injection of PC3 cells resulted in formation of large prostate tumors, while comparable injection of PC3 cells transduced with either one of two different USP3 shRNAs indicated that USP3 knockdown decreased tumorigenesis (Fig. 2H–J)."

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"In neuroblastoma patients, the m C reader ALYREF forms a nuclear coactivator complex with MYCN to stimulate USP3 transcription, which promotes the tumorigenesis of neuroblastoma (89)."

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"Suppression of USP3 blocked breast cancer cell tumorigenesis in vivo and proliferation in vitro ( Wu et al., 2019d ) ( Table 1 )."

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"USP3 knockdown inhibits subcutaneous tumorigenesis and distant lung metastasis in vivo."

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"Elevated USP3 levels further increase MYCN protein levels, contributing to neuroblastoma tumorigenesis."