IndraLab

Statements


YOD1 activates CDK1. 2 / 2
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reach
"Importantly, we are the first to have shown that YOD1 expression could induce CDK1 de-polyubiquitylation, thus revealing the potential underlying oncogenic role of YOD1.Rb, one of the important elements of E2F complex, is essential for coordinating the expression of CDK1 and CDK1-related cyclins."

eidos
"Finally , in vivo study demonstrated that YOD1 knockdown or YOD1 inhibitor could inhibit CDK1 expression and suppress the growth and metastasis of TNBC tumors ."