IndraLab

Statements

reach
"The adverse events surrounding the Phase I trials with TGN1412 led to the discovery of unexpected mechanisms related to CD28 activation in much the same way as the channelopathy, or long QT syndrome ([MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23954708
reach
"Intracellular K+ is required for the inactivation induced high-affinity binding of cisapride to HERG channels."
15967876
reach
"Thus, mutating these residues resulted in weak and loss of binding of cisapride to hERG, which led to poor inhibition of current in the mutant hERG systems."
33004839