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BAP1 inhibits response to stress. 3 / 3
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"BAP1 loss in UM leads to ASXL2 reduction and lipid homeostasis dysregulation, conferring lipotoxicity resistance and an enhanced oxidative stress response—an adaptation that can be exploited with atorvastatin, which induces lipid peroxidation and cell death specifically in BAP1‐mutant liver metastases (Figure 6)."