IndraLab

Statements


USP2 binds Cyclin and D1. 2 / 2
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"USP2 binds to Cyclin D1 and Mdm2 and induces their deubiquitination and stabilization, and its silencing causes downregulation of Cyclin D1 and Mdm2, leading to inhibiting cell proliferation."

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"By using co-immunoprecipitation approaches, we tried to determine whether elevation of O GlcNAcylation favors the binding of USP2 to cyclin D1, as described for BAP1 and PGC1alpha."