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OTUD3 inhibits Death. 2 / 2

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"Therefore, knockout of OTUD3 could upregulate the content of iron in dopaminergic neurons in the substantia nigra which, in turn, contributes to increased ER stress, and induces neuronal death and PD pathology."

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"Moreover, reconstitution of WT otud3 but not of otud3 -C70A or GFP mRNA in otud3 −/− embryos attenuated CyHV-2-induced death in otud3 −/− larvae ( Figures S9 D and S9E)."

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Statements

OTUD3 inhibits Death. 2 / 2

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