IndraLab

Statements

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"Downregulation of USP53 also promote cell proliferation in vivo."
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"USP53 Promotes Cell Proliferation in TNBC."
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"The results showed that knockdown of USP53 significantly reduced TNBC cell proliferation (Figure 2c,d,g)."
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"Overexpression of USP53 accelerated TNBC cell proliferation (Figure 2f,h)."
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"As shown, the knockdown of USP53 significantly reduced the proliferation of mouse mammary tumors (Figure 2m)."
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"Taken together, USP53 inhibited HCC growth in vivo by impairing cell proliferation and enhancing cell apoptosis."
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"Because upregulation of USP53 promoted proliferation, migration, invasion, and EMT in TNBC, we investigated whether this was due to the regulation of CRKL by USP53."
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"Cell proliferation assays showed that USP53 knockdown inhibited cell proliferation and increased chemosensitivity to PTX in MDA-MB-231 cells (Figure 7c)."
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"Consistently, USP53 overexpression promoted cell proliferation and decreased chemosensitivity to PTX in MDA-MB-468 cells (Figure 7d)."
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"Functionally, USP53 promotes TNBC cell proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT)."
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"Additionally, the knockdown of USP53 suppressed proliferation, EMT, and metastasis and enhanced the paclitaxel response of TNBC cells."
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