IndraLab

Statements


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"P62 and LC3A/B-II levels were increased at 7days, indicating the initial activation of autophagy and subsequent blockage of autophagic flux (Figure 1E)."

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"The LC3A and B-II expression levels, which drastically inhibited by rTF, rFVII or PAR2 activation, were fully rescued by mTOR knockdown in vitro, suggesting mTOR signaling pathway could have a key role in tumor malignancy through TF/FVII/PAR2 mediated suppression of autophagy."