IndraLab

Statements

OTUD5 inhibits IL17A. 2 / 2

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eidos

"OTUD5 inhibits the production of IL-17A by blocking the UBR5-mediated proteasomal degradation of RORgammat17 ."

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reach

"T-cell specific loss of DUBA therefore results in reduced levels of UBR5, stabilization of RORgammaT, and increased IL-17A production in response to TCR stimulation 76."

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INDRA sources:

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IndraLab

Statements

OTUD5 inhibits IL17A. 2 / 2

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