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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OTUD5 inhibits IL17A. 2 / 2

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"OTUD5 inhibits the production of IL-17A by blocking the UBR5-mediated proteasomal degradation of RORgammat17 ."

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"T-cell specific loss of DUBA therefore results in reduced levels of UBR5, stabilization of RORgammaT, and increased IL-17A production in response to TCR stimulation 76."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...