IndraLab

Statements


OTUD7B deubiquitinates KLF4. 3 / 3
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"Du et al. reported that OTUD7B attenuates cardiac hypertrophy by inhibiting KLF4 ubiquitination and degradation [20]."

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"These data indicated that OTUD7B interacts with and deubiquitylates KLF4 and OTUD7B downregulation by Sal-miR-1 and 3 attenuates KLF4 protein levels."

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"As anticipated, co-immunoprecipitation experiments revealed that OTUD7B interacted with and deubiquitylated KLF4."