IndraLab

Statements

reach
"Huang et al. confirmed that the converse is also true -- TAK1 inhibition by 5Z-7-Oxozeaenol (5Z-O) was associated with suppression of downstream signaling and CCR7 downregulation in breast cancer cell lines, resulting in decreased tumor growth and lymphatic invasion when tested in vivo in mouse axillary lymph nodes [XREF_BIBR]."
28858212
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"For TAK1 inhibition, BMDMs were treated with 0.1 muM 5Z-7-Oxozeaenol (TAK1i) for 1 h followed by LPS (100 ng/mL) post-treatment for the indicated times."
32547960
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"To better understand the molecular basis of this interaction, pharmacologic inhibitors SB43152 and 5Z-7-Oxozeaenol were used to inhibit the kinases of TbetaRI and TAK1, respectively."
29703898
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"TGFbeta activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage."
26100626