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Statements


COPS5 bound to E2F1 activates apoptotic process. 2 / 2
| 2

reach
"In addition, CSN5 specifically interacts with transcription factor E2F1 and enhances E2F1 dependent apoptosis by a mechanism that is independent of deneddylation activity [39]."

reach
"We previously showed that the E2F1 binding partner Jab1 and CSN5 promotes E2F1 dependent induction of apoptosis but not proliferation."