IndraLab

Statements


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"Similarly, inactivation of UCHL-1 in mice did not produce DA neurodegeneration, but did result in axonal dystrophy syndrome or motor ataxia [XREF_BIBR]."

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"All these findings seem consistent with a gain-of-toxic function of the UCH-L1 I93M mutant but little or no function of UCH-L1 wildtype or its lack in alphaSN induced DA damage."