IndraLab

Statements

USP7 inhibitors inhibits USP47. 3 / 3
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reach
"P22077 and P5091 are less selective USP7 inhibitors, also inhibiting USP10 and USP47 (27, 28)."
34965932
reach
"However, no specific USP47 inhibitors have currently been developed, although first-generation USP7 inhibitors, such as P5091 (1-[5-(2,3-dichloro phenylsulfanyl)−4-nitro-2thien l]ethanone) have been shown to inhibit both USP7 and USP47 with an IC of 4.2 µM and 4.3 µM, respectively, and antitumor efficacy in both in vitro and in vivo multiple myeloma xenograft models ."
37740002
reach
"Furthermore, some earlier USP7 inhibitors (e.g., P22077 and P005091) inhibit both USP7 and USP47 (Tian et al. 2011; Weinstock et al. 2012)."
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