IndraLab

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sparser
"Given our most recent studies indicating that HUR protein binds to USP8 mRNA and stabilizes USP8 mRNA [ xref ], and lncRNAs binds to their targeted protein and affects their bound protein function [ xref – xref ], we further probed the potential interaction between SNHG1 and HUR protein and the data obtained from the online analyses using catRAPID, RPISeq, StarBase V2.0 did suggest their interaction."

sparser
"Further studies revealed that ChlA-F treatment induces HuR protein expression and that the increased HuR interacts with USP8 mRNA, resulting in elevation of USP8 mRNA stability and protein expression."

sparser
"In non-small cell lung cancer, lncRNA SNHG12 bridges the interaction between USP8 mRNA and HuR, thereby enhancing the stability of HuR and achieving an increase in the expression of USP8 [ xref ]."

sparser
"Based on the HUR interaction with USP8 mRNA or SNHG1 , we postulated that SNHG1 might serve as a competitive endogenous RNA for USP8 mRNA by binding with HUR protein."

reach
"Direct binding of SNHG12 to HuR, as well as binding of PD-L1 and USP8 to HuR, was predicted using RNA–protein interaction prediction (RPISeq) (http://pridb.gdcb.iastate.edu/RPISeq/, accessed on 19 June 2023) and validated by RIP assay [151]."

sparser
"The database prediction indicated a comparatively high probability of HuR binding to USP8 (Fig.  xref A)."

sparser
"RIP assay further verified that HuR could bind to USP8 mRNA in NSCLC cells ( P  < 0.01, Fig.  xref B)."

reach
"Additionally, ChlA-F induced the expression of HuR, which binds to USP8 mRNA and increases its stability."

sparser
"Additionally, ChlA-F induced the expression of HuR, which binds to USP8 mRNA and increases its stability."

reach
"The scores of SNHG12 binding to HuR, and HuR binding to PD-L1 and USP8 were predicted using RNA–Protein Interaction Prediction (RPISeq) (http://pridb.gdcb.iastate.edu/RPISeq/) [29]."

No evidence text available

reach
"The database prediction indicated a comparatively high probability of HuR binding to USP8 (Fig. 5A)."

reach
"This interaction reduced HUR binding to ubiquitin-specific peptidase 8 (USP8) mRNA, causing degradation of USP8 mRNA and a subsequent decrease in USP8 protein expression."

reach
"Based on the HUR interaction with USP8 mRNA or SNHG1, we postulated that SNHG1 might serve as a competitive endogenous RNA for USP8 mRNA by binding with HUR protein."