IndraLab

Statements

PRKCE activates KCNH2. 2 / 2
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"We identified a specific role for the PKCepsilon inhibitory peptidomimmetics in decreasing PKC induced hERG tau activation (80%) and half-maximum activation voltage (90%) at steady state; a specific PKCepsilon activator exhibited the opposite effect."
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"Furthermore, over-expression of PKCepsilon enhanced current densities and promoted protein trafficking of hERG WT -hERG A561V channels."
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