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Mutation-Y652A inhibits KCNH2. 1 / 1

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"As shown in XREF_FIG, the pore mutation Y652A abolished hERG1 activation by 50 muM KB130015 at negative voltages, but the channels were blocked in an almost voltage independent manner to 63 +/- 4% (n = 9)."

20097192

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IndraLab

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Mutation-Y652A inhibits KCNH2. 1 / 1

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