IndraLab

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"Zn (2+) ions, which inhibit TRESK and TASK-3 K2P channels, decreased NT induced current."

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"Mouse TRESK expressed in COS-7 cells was also inhibited by Zn2+ and Hg2+, and TRESK single-channel current was diminished in outside-out patches, indicating that the action of the ions was membrane-delimited, most probably targeting the channel itself."