IndraLab

Statements


UCHL1 activates TRAF3. 2 / 2
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"However, UCHL1 mediated TRAF3 hampering could also lead to constitutive NIK accumulation and subsequent pathway activation."

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"The UCHL1 associated decreased detection of poly-ubiquitinated TRAF3 was not the result of increased TRAF3 degradation as blocking the proteasomal degradation pathway by the inhibitor MG132 did not result in a reappearance of poly-ubiquitinated TRAF3 (XREF_FIG)."