IndraLab

Statements


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"Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity."

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"Silencing USP15 inhibited MM cell growth both in vitro and in vivo."

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"USP15 has been shown to suppress glioblastoma cell growth through stabilizing the E3 ubiquitin protein ligase HECTD1 [17]."

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"Zheng et al. suggested that the ectopic expression of USP15 could suppress GC cell growth, migration, and invasion through the deubiquitination of IκBα by the COP9 signalosome (CSN) complex, thereby hindering NF-κB activity [40,142]."