IndraLab

Statements


EFEMP1 inhibits CYLD. 2 / 2
| 2

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"Then, as predicted, we observed that fibulin-3 overexpression downregulated CYLD mRNA whereas fibulin-3 knockdown caused the opposite effect (XREF_FIG)."

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"Therefore, we reasoned that fibulin-3 stimulation of Notch could downregulate CYLD and indirectly activate NF-kappaB."