IndraLab

Statements

JOSD1 decreases the amount of KRAS. 2 / 2
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"Correspondingly, depletion of JOSD2, but not JOSD1, significantly downregulated KRAS levels (Fig. 1e and Supplementary Fig. 1b, c), indicating JOSD2 positively regulates KRAS abundance."
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"However, neither JOSD1 wild-type nor its enzymatic mutant failed to decrease KRAS polyubiquitination levels (Fig. 2g)."
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