IndraLab

Statements


Phosphorylated RPS6KB1 phosphorylates RPS6. 7 / 7
1 | 6
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"It has been well established that activation of PI3K/Akt/mTOR pathway leads to phosphorylation of p70S6 kinase, which subsequently induces the phosphorylation of ribosomal protein S6."
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"In particular, phosphorylated p70S6K enhances phosphorylation and activity of ribosomal protein S6 and initiates various translation activities required for cell growth."
biopax:panther
No evidence text available
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"Phosphorylation of p70S6K stimulates its phosphorylation of ribosomal protein S6, initiating a variety of translation associated activities."
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"Activated mTOR phosphorylates p70 ribosomal protein S6 kinase (p70S6K) followed by p70S6K induced phosphorylation of ribosomal protein S6 and eukaryotic initiation factor 4B (eIF-4B) which promotes the initiation of protein translation."
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"It is known that mTOR phosphorylates p70S6K followed by p70S6K induced phosphorylation of eIF4B and S6 (XREF_FIG)."
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"Both the phosphorylated p70S6K and phosphorylated rpS6 expression were reduced in the FulvC2 as compared to the parental and other sublines."