"It has been well established that activation of PI3K/Akt/mTOR pathway leads to phosphorylation of p70S6 kinase, which subsequently induces the phosphorylation of ribosomal protein S6."
"In particular, phosphorylated p70S6K enhances phosphorylation and activity of ribosomal protein S6 and initiates various translation activities required for cell growth."
No evidence text available
"Phosphorylation of p70S6K stimulates its phosphorylation of ribosomal protein S6, initiating a variety of translation associated activities."
"Activated mTOR phosphorylates p70 ribosomal protein S6 kinase (p70S6K) followed by p70S6K induced phosphorylation of ribosomal protein S6 and eukaryotic initiation factor 4B (eIF-4B) which promotes the initiation of protein translation."
"It is known that mTOR phosphorylates p70S6K followed by p70S6K induced phosphorylation of eIF4B and S6 (XREF_FIG)."
"Both the phosphorylated p70S6K and phosphorylated rpS6 expression were reduced in the FulvC2 as compared to the parental and other sublines."