IndraLab

Statements


4 | 2

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"In dextran sulfate sodium-induced colitis mice, OTUD1 binds to RIPK1, removing K63-linked polyubiquitination and inhibiting NF-κB activation, reducing pro-inflammatory cytokines and preventing colitis [ xref ]."

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sparser
"The OTUD1-RIPK1 axis may be mediated by inhibiting NF-κB activation to regulate intestinal inflammation [ 38 ]."