IndraLab

Statements

USP5 inhibits Notch. 3 / 3
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"Loss of Usp5 results in upregulation of Notch signaling and downregulation of RTK signaling, leading to impaired photoreceptor development."
28140449
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"In addition, USP5 negatively regulates the Notch and RTK signaling pathways by inhibiting Jun N-terminal kinase (JNK) [46,51,52]."
38927085
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"The loss of the deubiquitinating protein Ubiquitin carboxyl-terminal hydrolase 5 (Usp5) leads to the upregulation of Notch during Drosophila melanogaster eye development [XREF_BIBR]."
31301363