IndraLab

Statements

Curcumin inhibits FOS. 7 / 7
| 7
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"XREF_FIG shows that curcumin selectively inhibits the transcriptional activity of c-Jun and c-Fos but not c-Jun and Fra -1 in the absence of exogenous Zac1 (XREF_FIG; closed bars)."
26633653
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"Most interestingly, curcumin can reverse the expression dynamics of c-fos and fra-1 in this tumorigenic cell line, mimicking the expression pattern observed in normal controls or precancerous lesions."
15514944
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"Curcumin at 20/^ M inhibited nearly all the TEA induction of c-Fos elevation."
7553596
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"Curcumin can also reverse the expression dynamics of c-fos and fra-1 in tumorigenic HeLa cells by mimicking their expression pattern in normal cells."
| PMC
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"In this study, we show that curcumin decreases the TPA- induced c-Fos elevation in the nuclear extracts in spite of the slight super-induction of c-fos mRNA."
7553596
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"Furthermore, curcumin reduced the intracellular signaling proteins Ras, B-raf, p-MEK, p-ERK, c-fos, Egr-1, but increased Raf-1 and NAB2 in MDCK cells exposed to forskolin."
21187084
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"Curcumin could attenuate the activation of p-ERK, p-CREB, c-fos in dorsal root ganglion to ameliorate the CCI-induced neuropathic pain."
21155252