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Histamine inhibits NLRP3. 3 / 3
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"A recent study in neuroscience showed that a histamine H1 receptor agonist, 2-(3-trifluoromethylphenyl) histamine (FMPH) reduced the production of NLRP3/Caspase-1 so that inhibited the pyroptosis of a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Moreover, treatment with a histamine H receptor agonist, 2-(3-trifluoromethylphenyl) histamine, reduced the antipsychotic-induced activation of NLRP3/caspase-1 signaling and astrocyte death."
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"In contrast, HSM reduced ASC and NLRP3 mRNAs in a statistically significant manner in the lungs of BLM treated mice when examined on day 21 (XREF_FIG)."
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