IndraLab

Statements

MAP3K7 binds USP43. 7 / 7
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"Our study revealed a direct interaction of USP43 with TAK1."
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"USP43 binds to TAK1 and inhibits the degradation of TAK1."
41088415
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"In Usp43 -overexpressed primary neurons, TAK1 also binds to USP43 (Fig.  xref b)."
41088415
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"Furthermore, the GST pull-down assay confirmed a direct interaction between USP43 and TAK1 (Fig.  xref d)."
41088415
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"Our study suggests that USP43 interacts with TAK1 through deubiquitination of the K48 link during cerebral ischemia–reperfusion injury, activating the downstream JNK/p38 signaling pathway."
41088415
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"Molecular mapping analyses were then performed to identify protein structural domains associated with USP43 and TAK1 binding."
41088415
sparser
"It was found that USP43 interacted with TAK1 and inhibited the ubiquitination on TAK1 (Fig.  xref b)."
41088415