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Mutated CACNA1D activates aldosterone. 2 / 2

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"In line with the notion that these effects will lead to increased calcium entry, expression of mutant CACNA1D channels causes increased aldosterone production in the adrenocortical cancer cell line H295R."

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"However, it is important to note that only part of the CACNA1D mutations were functionally characterized to increase aldosterone production by in vitro studies."

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IndraLab

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Mutated CACNA1D activates aldosterone. 2 / 2

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