IndraLab

Statements

CYLD inhibits MYD88. 3 / 3
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reach
"Thus, CYLD inhibits MyD88, RIP1 (receptor interacting serine/threonine protein kinase 1), TRAF2, TRAF6, TRAF7 and NEMO downstream to TLR signaling and regulates exaggerated inflammation which can lead to the development of severe infection causing sepsis and associated organ damage."
| DOI
sparser
"Thus, CYLD inhibits MyD88, RIP1 (receptor-interacting serine/threonine-protein kinase 1), TRAF2, TRAF6, TRAF7 and NEMO downstream to TLR signaling and regulates exaggerated inflammation which can lead to the development of severe infection causing sepsis and associated organ damage."
| DOI
reach
"Deubiquitinase CYLD negatively regulates MyD88 mediated signaling by directly interacting with MyD88 and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63 linked polyubiquitination of MyD88 at lysine 231."
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