IndraLab

Statements

CYLD inhibits MYD88. 7 / 7
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"Recent studies suggest that CYLD negatively regulates MyD88-mediated signaling by the direct deubiquitination of MyD88 at Lys231 (Lee et al., 2016)."
36152458
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"Thus, CYLD inhibits MyD88, RIP1 (receptor interacting serine/threonine protein kinase 1), TRAF2, TRAF6, TRAF7 and NEMO downstream to TLR signaling and regulates exaggerated inflammation which can lead to the development of severe infection causing sepsis and associated organ damage."
| DOI
sparser
"Thus, CYLD inhibits MyD88, RIP1 (receptor-interacting serine/threonine-protein kinase 1), TRAF2, TRAF6, TRAF7, and NEMO downstream to TLR signaling and regulates exaggerated inflammation which can lea[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
33075714
reach
"Thus, CYLD inhibits MyD88, RIP1 (receptor-interacting serine/threonine-protein kinase 1), TRAF2, TRAF6, TRAF7, and NEMO downstream to TLR signaling and regulates exaggerated inflammation which can lea[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
33075714
reach
"Deubiquitinase CYLD negatively regulates MyD88 mediated signaling by directly interacting with MyD88 and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63 linked polyubiquitination of MyD88 at lysine 231."
26719415
sparser
"Thus, CYLD inhibits MyD88, RIP1 (receptor-interacting serine/threonine-protein kinase 1), TRAF2, TRAF6, TRAF7 and NEMO downstream to TLR signaling and regulates exaggerated inflammation which can lead to the development of severe infection causing sepsis and associated organ damage."
| DOI
reach
"CYLD inhibits STAT1, MyD88, and NOD2 signaling in S. aureus-infected M1-polarized macrophages."
39958342