IndraLab

Statements

Nitric oxide inhibits JUN. 5 / 6
| 5
reach
"Nitric oxide inhibits IgE dependent cytokine production and Fos and Jun activation in mast cells."
15557187
reach
"NO attenuated the binding of activator protein-1 to the 12-O-tetradecanoylphobol-13-acetate-responsive element (TRE) in the MCP-1 promoter region."
11742868
reach
"Furthermore, in both models of apoptosis, NO releasing compounds dose-dependently reduced : (a) the number of the titratable thiol groups (cysteine residues) of c-Jun; (b) induction of AP-1 DNA binding activity; (c) AP-1-driven transactivation of the CD95L promoter; and (d) caspase activation."
10811113
reach
"According to a recent study of Sarkar, NO can inhibit JNK1 (c-Jun N-Terminal Protein Kinase1) and IKK (I Kappa-B Kinase) via mTOR (mammalian target of rapamycin) and mTOR-independent pathways, respectively, to prevent autophagy."
39840143
reach
"NO prevents the activity of Jun N-terminal kinase1 (JNK1) by S nitrosylation that leads to reduction in Bcl-2 phosphorylation."
26330869