
IndraLab
Statements
Nitric oxide inhibits JUN. 4 / 5
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4
reach
"Furthermore, in both models of apoptosis, NO releasing compounds dose-dependently reduced : (a) the number of the titratable thiol groups (cysteine residues) of c-Jun; (b) induction of AP-1 DNA binding activity; (c) AP-1-driven transactivation of the CD95L promoter; and (d) caspase activation."