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USP29 inhibits K48-linked ubiquitination degradation cGAS. 1 / 1
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eidos
"Consistent with the notion that USP29 deficiency promoted K48-linked ubiquitination and degradation of cGAS , we found that treatment of MG132 but not 3MA fully prevented the degradation of cGAS in Usp29m / m MEFs in the presence or absence of HSV-1 infection ( Fig. 6g ) ."