IndraLab

Statements

P5091 inhibits USP47. 2 / 2
| 2
eidos
"Our initial USP7 inhibitor , P5091 , is not specific to USP7 but additionally inhibits USP47 ( ubiquitin-specific peptidase 47 ) , which , among several functions , controls tumor cell proliferation ( 38,39 ) ."
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eidos
"Since the previous studies have demonstrated that P5091 also inhibits Usp47 activity , we chose other specific Usp7 inhibitors ( Usp7-IN-155 and HBX-1981856 ) to validate our results ."
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