IndraLab

Statements

Notch inhibits CYLD. 3 / 3
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"Therefore, we reasoned that fibulin-3 stimulation of Notch could downregulate CYLD and indirectly activate NF-kappaB."
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"Similarly, CYLD is downregulated by Notch and Hes1 in T-cell acute lymphoblastic lymphoma (T-ALL), thus leading to constitutive NF-kappaB activation."
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"Notch activation in CYLD siRNA transfected cells was normalised to cells transfected with non silencing siRNA."
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