IndraLab

Statements

USP24 inhibits TP53. 4 / 5
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"However, some groups also demonstrated that USP24 prevents P53 from degradation to regulate the DNA damage response 23."
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"Knockdown of USP24 failed to prevent stabilization of p53 following etoposide treatment of H4 cells), suggesting that in this cell type USP24 may be dispensable for DNA damage responses or that the very low residual USP24 protein may be sufficient."
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"However , some groups also demonstrated that USP24 prevents P53 from degradation to regulate the DNA damage response 23 ."
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"Depletion of USP24 significantly attenuates p53 dependent apoptosis induced by DNA damage."
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