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OTUD4 decreases the amount of GSDME. 2 / 2
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"Finally, we confirmed the clinical relevance of the OTUD4/GSDME axis, and patients with low OTUD4 expression also had reduced GSDME levels."
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"As expected, upregulation of OTUD4 distinctly increased, while OTUD4 knockdown reduced, the GSDME protein level (Fig. 5H)."
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