IndraLab

Statements

USP7 inhibits autophagy. 3 / 3
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"Silencing of KDM6B reversed the promoting effect on autophagy and proliferation induced by overexpression of USP7."
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"43 In conclusion, our study demonstrated that up-regulation of miR-15b could inhibit the expression of USP7, which potentially suppress the osteoblast proliferation, differentiation and autophagy to aggravate osteoporosis through inhibition of KDM6B expression."
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"Elevated levels of miR-15b in osteoporosis inhibit the USP7/KDM6B axis, thereby suppressing osteoblast differentiation and autophagy, exacerbating osteoporosis."
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