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ATXN3 activates Protease. 2 / 2
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"Here, we report that ubiquitination of the DUB ataxin-3 at lysine residue 117, which markedly enhances its protease activity in vitro, is critical for its ability to suppress toxic protein dependent degeneration in Drosophila melanogaster."
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"Based on their features, DUBs can be categorized into at least seven subfamilies : ubiquitin specific protease (USP), ubiquitin C-terminal hydrolases protease (UCH), Machado-Joseph disease protein dom[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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