IndraLab

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"14 A small pilot study in patients with pruritus from undefined etiologies demonstrated that topical application of hydrocortisone acetate 2.5% and pramoxine hydrochloride 1% in a hydrolipid lotion reduced pruritus by 30% from baseline as rated by patients using the visual analog scale within 24 hours of initiation of therapy."

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"52 Pramoxine, which is thought to exert anti-pruritic effects by stabilizing membranes of sensory nerves, effectively decreases itch in patients with xerosis, uremic pruritus, and psoriasis and has been used as a single agent or in combination with mild potency topical steroids or lactic acid lotion."