IndraLab

Statements

USP9X inhibits meiotic spindle assembly checkpoint. 2 / 2

| 2

reach

"In the presence of many unattached kinetochores, the SAC signal is strong and therefore, although USP9X depletion reduces SAC efficiency in cells arrested in mitosis with nocodazole, the arrest still persists for several hours (XREF_FIG B)."

29669289

➶

reach

"We demonstrate that depletion or loss of USP9X reduces the effectiveness of the SAC, elevates chromosome segregation defects, and enhances chromosomal instability (CIN)."

29669289

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP9X inhibits meiotic spindle assembly checkpoint. 2 / 2

INDRA sources:

Databases

Reading