IndraLab

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CYP51A1 increases the amount of KCNH2. 2 / 2
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"Inhibition of a later step in the ergosterol biosynthetic pathway by ketoconazol, an inhibitor of the lanosterol-14alpha-demethylase (encoded by ERG11), also induces the expression of ERG1, indicating that ERG1 expression is positively regulated by diminished intracellular ergosterol levels."

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"Inhibition of later steps in the ergosterol-biosynthetic pathway by ketoconazole, an inhibitor of the lanosterol-14alpha-demethylase, and U18666A, an inhibitor of the squalene-2,3-epoxide-lanosterol cyclase, also induce expression of ERG1, suggesting that ERG1 expression is positively regulated by diminished intracellular ergosterol levels."