IndraLab

Statements

reach
"Inactivation of BAP1 in cancer cells results in evaluated SLC7A11 expression, increased cystine uptake and GSH synthesis, and enhanced ferroptosis resistance, which contributes to tumor development."
38089453
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"The large number of genome editing tools and techniques available for E. coli [60,61] allow quick and precise manipulation of this organism for biotechnological applications.In the context of NP biosynthesis in E. coli, metabolic engineering has been used to build chassis strains such as HM0079 and BAP1, that are optimized to support the synthesis of complex NPs by expressing phosphopantetheine transferase, an enzyme crucial for the function of the polyketide synthases and nonribosomal peptide synthetases [9,10]."
36196987
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"These results highlight a mechanism by which BaP1 induces PGE biosynthesis and suggest that activation of mPGES-1 gene expression is the primary mechanism leading to an increase in this protein."
32094439
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"As activation of this receptor by PGE can induce synthesis of other inflammatory proteins, including COX-2 and mPGES-1, we investigated the involvement of EP4 in BaP1-induced effects."
32094439