IndraLab

Statements

USP24 inhibits IKB. 3 / 3
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reach
"beta-TrCP overexpression in USP24-knockdown cells prevented the upregulation of DNMT1and IkappaB induced by USP24 knockdown and demonstrated that beta-TrCP is critical in the USP24 induced increase of DNMT1 and IkappaB expression."
30266897
reach
"In this study, we discovered the underlying mechanisms by which USP24 not only promotes IkappaB degradation by stabilizing beta-transduction repeat containing E3 ubiquitin protein ligase (beta-TrCP) in lung cancer cells but also induces the upregulation of NF-kappaB in M2 macrophages, resulting in an increase in IL-6 expression."
30266897
reach
"USP24 decreases DNMT1 and IkappaB through stabilizing beta-TrCP."
30266897